Defect in retinal computation linked to congenital nystagmus

By: | Tags: , , | Comments: 0 | January 6th, 2016

A clearly defined neuron type has been identified, along with its circuit in the retina in the pathophysiology of idiopathic congenital nystagmus. In a mouse model of the disease, which shows similar clinical symptoms as patients, a defect in starburst cells elicited by dysfunctional FRMD7 leads to the loss of the horizontal optokinetic reflex.

      

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